Cranio-maxillofacial surgery, including frontal sinus obliteration

Several long term studies, extending over 10 years of patient follow-up, have shown that BonAlive® granules generate outstanding clinical results in bone cavity filling applications in the cranio-maxillofacial area. The main applications of BonAlive® granules are filling of benign bone tumour cavities, filling of the osteotomy site in bilateral sagittal split osteotomies, fronto-orbital trauma and frontal sinus obliteration.

Most conditions of the frontal sinus requiring surgery can be treated successfully by endonasal or nasofrontal duct reconstruction procedures. However, in certain difficult cases, optimal exposure of the entire frontal sinus area is essential. Frontal sinus obliteration can be a treatment alternative for such frontal sinuses.

The unique bacterial growth inhibiting feature of BonAlive® granules gives distinct advantages in areas that are postoperatively prone to infection.


  • Bone cavity filling in cranio-maxillofacial area including the jaw
  • Frontal sinus obliteration after severe chronic sinusitis or fractures in the frontal bone area

For further details see references.